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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '48279719efdf5636f0f9bf3cecad74a5eddcf2baedfc8f8ff7185cd4a5881b1f' 
  AND token = 'bHRu+HQO7CDbTcLY8vhYcrwlmLlFEDFMaOO/lO4FB+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}