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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '144ea09226f8c23cc7f38348f08497232a39379cf23e8f0d2e0c7da88ac0b09f' 
  AND token = 'tsO+n/pbK8b9dtqT0x5tnyDzcdkqyK74KYXp/hAGUKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}