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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9246b5749503fbb7af58143febd4253e4fce194c1045e684e0ba7077eb43d177' 
  AND token = '3k/LtIhCLNQozNfkjDYq/OUbEt62OGfQl55E0dKtrpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}