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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '33ee22c0f5bc6dcdeaa6c55a97d99a4d4ac36275bfb4df7d3b63fa5d5f4af39f' 
  AND token = '7cbwcHTITTK4khGfCSQxpBsFMe0HIcKMIJZPhnndZSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}