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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e3b674983846d123fcf592198a27983262e13a9d1c007022a9c28cd125f22be' 
  AND token = 'IPik0JkMa+9TlUtxQ/F+Lx0cG5Al4pV8znp1ptScI2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}