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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '39e307e6c24a0de1fcd0b1de206cf59a40c12851e93d877e1e19779817f1b249' 
  AND token = 'DSrnrqcnwcapaOPUkEXac5NUSSsjjNWzT32mhLAbXGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}