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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '728594275fdad9ff5c27a4be60b996a1f596cb989b9c4e4de03f8ccea1bb0eb8' 
  AND token = 'nNZkMKtkJl2+1ZBQwL2bGXWxmP9mLArGa9FJ+EmsCQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}