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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '25c5df4314fbe9248b2801ff1a4f1e09759bd4d135ff8d24a37d95db91f92f32' 
  AND token = 'TYmflK/1g5UoaSIYl/+0nB7gnNBVP3m1Ut0FZt8eNLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}