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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '75062a974eff7aea42d94562d9e49c94b419b6b013b1478c979e4bd4e5838df4' 
  AND token = 'XNcUR+XNy2aSJF8dzgHHacJdmuSt/EAbmOwkN5SDbAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}