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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65250c9c18be48373f2d19383350a3e85d14975ed873de154414027b837b3a4e' 
  AND token = 'tEXPar2tP+ZGbry17L3cN0VPPcJ0JZqVWOirmPQbcJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}