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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1c5c9fb148ac5b01d378236ddcfb77818a17723411691e81fa49904c0e980419' 
  AND token = 'p5/1SDLwL/CB9AA5q2DrwySI8kqqXMlKAm7tiSP3KT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}