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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0e50295c24a7af535daccf32d47479660f7b0f54397e0fd79004d668693e08e1' 
  AND token = '9tctTdOnL7CbHvSAGdO5z/NdtTGGcv2oUPqxGXHhvtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}