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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e9272067b7779c29c357f72cdc46d06e0ed0505a7fbdd8a50544e0538060404' 
  AND token = 'MrDD0OCvTLfEZaQq/JeQZyI4IZsOHUyjTae7yfqYPZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}