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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '37fb78f0543fc3e7ab4f20c204426f4945527f92432dc5ede7a17338a9522ac9' 
  AND token = '49amob6q6+sDIUR7BWyQ2s2bfth4Mb8wT38B6SU6kfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}