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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4c00c9e114a661fe53878d9862d29277525ef63d323015c04a0c5ec5e1ee2639' 
  AND token = 'YaFqQ2ZJlS1amr3Veq9JQuJ1l1FJRE8eW0sIGSlm7HQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}