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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'dbe48d78cce26440ff90749f58f3d4646454e0a0aa1fa7e69162e79885afde61' 
  AND token = '/ejXN4fSyf9xFDwOzXOM1m7r2+9t7nNTKg0mvaQMZ4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}