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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1b4434d4fbb47c71f08769de6b2418e3748279dfb1352331a95008df8a0d7549' 
  AND token = 'RsikHTtHWgux9OMcAgUH4Y0gwXdIEQZ1b1jZ6RwCuj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}