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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '50b74e50b9a028eaaaa2a55710f29d4022fe584ecd82149af684812bc02df98d' 
  AND token = 'Ku8LDZkpi02nD6p+C1TdcjuHZg+Y+hkTBcRoDuvG9rY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}