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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '578d7c528991465f47817a45ab114c4ea58263332211c1481a71b5ab9ade3538' 
  AND token = '8byCVi84/B0G7ZpScBqI+4MXJsALASxcl3H6h3IdbtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}