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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49e2f6f41d75a6c89507db40b6981816122883966bd56be8f5daf566d7fddaa0' 
  AND token = 'mC+YMmxDknyMDk+nAb5cE4EhySkngMSzldExz7JsFSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}