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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cea19385092934cf843378afc7386dd3f92686e9eee53f6f28ef175c28e11106' 
  AND token = '6wksSaBxzdrfWhpoka2BX1/NFxvXRrjeMZTUtSJnBAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}