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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '57a99aaa735e011b723871f07b2fdb79f1f0d079ca02d005c38343da25d494dd' 
  AND token = 'ORADoYxD3e7Je6WV/ZfTSlg/hnB8gDfgeRuUHiqUWTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}