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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e5e0383126760b7496a8ab26ccad2418e7d8719fb6e5c6cd3305aef4cac504f' 
  AND token = 'TIRhkmNRDTfeOa8mQMX57tk/uIKrvdpVXSzkN/cVwfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}