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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ee2b46a66376f855069279dd2f2febf6ffc75a4ca43c659ae0928352bec74fb8' 
  AND token = 'W5iCFHkAPTmODM4f3yQNNJjFR1SRdbzuHOcUNAc3mTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}