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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd49c79f19a8acf2efe8618238ac8eb4879dacbeef20ef958e9d147c969c63fb4' 
  AND token = 'q1cGsq9W2vrUAawwZvaeVkCuFQgcsGgGWFcKqzZ9DEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}