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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46516f19dc45d00644cd2708ba815402100648b79f859a00cc0f3b8201a824d1' 
  AND token = 'sdfgA9O6gxH+LMGB81u2/rYgGiGMFa0BnW2k8BQNObA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}