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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5cdbeaa03bd539e1c6f5010c8fd8cd870c1d7c884d0dfd136095f0151af90438' 
  AND token = 'tT+KWD9KXjTBR8weMI14B6Fd8ciFuAgm5XDAAxMhRv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}