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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3427272ab7cc17cd3b7f43400bc57f08361341e8afa1a4e24e4c736520fb24fc' 
  AND token = 'RwFQHJlqSb5/Z5I8UEvYFM4095O5h6nItFaOWmnGAqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}