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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f65cd9e7dfec9ff7a78c791b81a1636c4869ae84425dda8f08d50cc89e2c62ae' 
  AND token = '18FDrF1/fuvktBiKc++tFKPLDnSrn5qnkhSXwnM//ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}