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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cad288c298614aca3b4fe2d9d350cdc6a8364b2f6eff1e505d2ca7f2c9c29311' 
  AND token = 'mJsWoQ+RZE5HyDWYZS3KpZirhhchLaaW5QmoBCYhMG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}