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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '309f54adfb1011d08fea711c95ca589611695a607faaf2614ccf237a03c7a6b5' 
  AND token = 'uOTuBhqUJFth+P1CTnvEZX4HTG4kZxsf4oaG6D0Aa68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}