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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0d53b755e95a24bafc1011f5e4725f81340390a41d87f7a156cdb89a84b2d1a0' 
  AND token = 'BBmiTWQqp8kJPDbTxXGsdYUVx8d7EmUrxAJwaIclMo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}