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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '213165128a69eada0501b747cdb7e2461c3fb525b491d841a1271ed3fe2dd148' 
  AND token = 'JXBwDAMUNRE72nuEFEqUxV9tBOm/S1CEj2YgIMIfXd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}