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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a09e9ec2d33c36b02e832eb70119d612cf5a4011149b577506b9a7bf7ae540d1' 
  AND token = 'xbwQmH72uw8F7r+khxS2D1noABOBl1KqVFt6MgAaAOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}