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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8965cf20ecef972a38f34b6c18aa7f34cfb52e42c3167903793e1b21de5e9328' 
  AND token = 'NdmNXlbgXp6l8hVj5QMzGDr4rBUybI9VE38ZiiL9qkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}