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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a4b9cac243fa404322d9572922b9ef193f03be7a6e48d84c5a6da86551f4631' 
  AND token = 'PzIAN4hFEx58dHbAUNByolNO5nCc6SAHwSh73faiIIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}