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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '874122cd8fa6c7376cc4415f353bf1f3a462da1a6d394e60a1e2d99d50b3171d' 
  AND token = 'nLtNOCjK6z/ytVaF2FB5/vRnGnG+66aiwi5RGc1SMjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}