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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7c94c75e78dd488b2b9f39bf905d4545ca858e7fe6bffc21ea5d9892c3f3bbef' 
  AND token = 'DBm/s4uyHoHjlZ1WR47d7dCkb9PIKao2xNqQkh1aVys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}