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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b044219d331e3c75257a2b403064cbb3dddb3dd6e7f57ea9d2d6c1c125cd8c8' 
  AND token = 'MO6lFj2gXzjad1LgbXedd4Ubm+hYBZ3JnF75tg/vQxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}