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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c16745ba1364a5c826185a95f475953a435e867d09644fae054f4cfa3869d657' 
  AND token = 'M9M61xfUIWnUanbEMTSyiSxzEphGhXH7gfG4t+oRPeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}