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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65a60e958fd8ed2ab266fe8dac5a33477d06668fee9fb68f34610597cc9b3574' 
  AND token = 'xAi1QKi0XYB+/o2hVV6717At2nSk025bRUYphQXCIK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}