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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0d2051ad933181ab7c2a3723cb1ee8024ece55b78e8766fc92c972ef1380145e' 
  AND token = 'v29xVdLplhlVJBFS2f3C+lIC+sr8IXoOFfkCRAQjFdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}