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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '457351eccbcc1cc0ed63d28992af2b8b95b94596d25e5c4953186e05ee188728' 
  AND token = 'RK+APrQ9IirtllfT+IXVhiU7A5ejjeayVOEaQiVscWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}