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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b4dc16f0b5712d458f84bee10a379a8d25ad5fb11505b94522016f7b88e31389' 
  AND token = 'keWx8RvLsRA8p/zz5g3eHhNW1fxVRXEAk3aRyfGyFg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}