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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a2937bfa72ffdaf195a1b7ede4ac13d542ff9c137dfef3949e3c83844e7358d3' 
  AND token = 'COnZfq9ZK6uh3RromF/oLfm0594zUd92v3tx78YizBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}