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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6e06a1e1198833055fbdceef97105d7f04def46c49033b667e5d086d1e68f6d2' 
  AND token = 'XGXV1hrz2ydh1KVMckMMyD6LHVxzlCPTJdfqGGZQfSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}