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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'bcb00ea1b35841815a950476d7fed367cac1584dbb14167e975c9ca9f16f2a1e' 
  AND token = 'PC6GtGSfVGpxvpTUPePaTjyvS1thrrs2hrV+qli35yA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}