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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '24226e51364c4c2ec3646e6b239947df58612d55d05af5ee50999accf52de642' 
  AND token = '2C/jCsoUIeJOiJmM7Pw8VIJDmLEIKU9VDLZY6PEJNcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}