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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22b189b34abdd3d58479c5a9ea05eacf32d527296453cd6b93f3a43a9d7dfdbe' 
  AND token = 'Ck2RUBtIfiSE7dcAczkC7YtGmS+0F0gSORQTMDs7myc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}