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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f4762ef8ad074589f8c200df1b1ac3570f06aad28010eb610ad4f7017939a369' 
  AND token = 'PE+2QpbV7s+vLZCtk1h3kK2BW8cR575Ur9OuC2y8Y7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}